ISOThrive Inc. is a Clinical Stage Biotech Company

Microbiome Therapeutics

Treating Chronic Disease Caused by Microbiome Dysbiosis

We develop novel, proprietary digestion-resistant carbohydrates that target specific bacteria to correct microbiome dysbiosis.  Correcting dysbiosis is a potentially disease modifying MoA in numerous disease states of high unmet need. 

The company’s lead asset, ISOT-101, is a Ph2 ready maltosyl-isomaltooligosaccharide (MIMO). 

Assets

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MIMO:
A “Keystone” microbiome carbohydrate

ISOT-101 a novel patented and patents-pending prebiotic therapeutic. 

It is a proprietary digestion-resistant carbohydrate, maltosyl-isomaltooligosaccharide (MIMO), which is an energy source for targeted beneficial bacteria. 

Initial indications include GERD, IBS-C and Functional Dyspepsia.

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Lightning™ Rapid Carbohydrate Drug Discovery Platform

Different bacteria prefer different types of carbohydrates. 

With our Lightning Rapid Carbohydrate Drug Discovery Platform, we can create a differentiated pipeline of novel MIMO’s targeting any number of GI conditions, both upper and lower GI profiles

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Rosetta™ Microbiome Precision Medicine Platform

Information on the abundance of metabolic functions possessed within a given bacterial community coupled with knowledge of their microFood™ preference hierarchies enables us to algorithmically select the ideal microFood™ blend to achieve a beneficial activity shift to (a) alleviate disease or, (b), achieve more optimal health.

 

Pipeline

 
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