
ISOThrive Inc. is a Clinical Stage Biotech Company
Microbiome Therapeutics
Treating Chronic Disease Caused by Microbiome Dysbiosis
We develop novel, proprietary digestion-resistant carbohydrates that target specific bacteria to correct microbiome dysbiosis. Correcting dysbiosis is a potentially disease modifying MoA in numerous disease states of high unmet need.
The company’s lead asset, ISOT-101, is a Ph2 ready maltosyl-isomaltooligosaccharide (MIMO).
Assets
MIMO:
A “Keystone” microbiome carbohydrate
ISOT-101 a novel patented and patents-pending prebiotic therapeutic.
It is a proprietary digestion-resistant carbohydrate, maltosyl-isomaltooligosaccharide (MIMO), which is an energy source for targeted beneficial bacteria.
Initial indications include GERD, IBS-C and Functional Dyspepsia.
Lightning™ Rapid Carbohydrate Drug Discovery Platform
Different bacteria prefer different types of carbohydrates.
With our Lightning Rapid Carbohydrate Drug Discovery Platform, we can create a differentiated pipeline of novel MIMO’s targeting any number of GI conditions, both upper and lower GI profiles
Rosetta™ Microbiome Precision Medicine Platform
Information on the abundance of metabolic functions possessed within a given bacterial community coupled with knowledge of their microFood™ preference hierarchies enables us to algorithmically select the ideal microFood™ blend to achieve a beneficial activity shift to (a) alleviate disease or, (b), achieve more optimal health.
Pipeline

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